Helping Aging Patients Feel Their Best

The importance of telomeres: 

Telomeres are nucleoprotein structures which serve as the biological clock of cells and organisms in the body – they act as the protective mechanism at the end of our chromosomes. Telomerase is an enzyme responsible for synthesizing and determining telomeres length. The length of telomeres shortens with each round of cell division. Research has shown aging has an affect on telomere length as older individuals have shorter telomeres, affecting cell and tissue health.[1] Telomere length is correlated with age and metabolic status; the rate of which telomeres shorten can also indicate the pace of aging.[2] 

Stem Cells and Healthy Aging:  

Stem cells are undifferentiated cells which have the unique ability to develop into specialized cell types within the body. Stem cells are essential as they enable the healing and replacement of dead cells every day. These regenerative cells are important for aging as tissue homeostasis and regeneration depend on these healthy adult stem cells.[3] 

During the natural aging process, the functionality of adult stem cells and the ability to self-renew declines. Stem cells’ response to oxidative stress can further accelerate this decline as oxidative stress results from an imbalance between antioxidants and reactive oxygen species (ROS).[4] 

Developing a plan: 

While aging is a natural process that affects every cell and organ, the rate at which mental and physical health decline are the most significant factors when it comes to quality of life and longevity. Patients aged 65 years or older make up over 30% of acute care hospitalizations and 50% of hospital visits.  

Tried and true staples such as vitamin D and calcium often come to mind; they both have significant clinical evidence showing  how they support immune health, healthy bones, and joints.[6],[7] Vitamin D3 plays a vital role in supporting immune and bone health; additionally, higher vitamin D levels may reduce telomere shortening.[8] Antioxidants, dietary phytochemicals (polyphenols and flavonoids), and targeted enzymes can all have a place in a nutritional aging protocol and perhaps help turn back the clock.[9] 

Blueberry and green tea extracts are rich in polyphenols, and have been shown to support cognitive function and promoting healthy stem cells. [10],[11] The benefits of enzymes have been known for thousands of years as they play a crucial role in the digestion of nutrients (digestive enzymes), protecting cells from free radicals (antioxidant enzymes), and mediating damaged proteins (proteolytic enzymes).[12] 

Many variables can influence the aging process. Physical activity (including strength training exercises), a healthy whole-foods based diet and adding in targeted nutrients can support your patient’s quality of life and the normal aging process.